Magnesium in depression.
Pharmacol Rep. 2013;65(3):547-54.
Serefko A, Szopa A, Wlaź P, Nowak G, Radziwoń-Zaleska M, Skalski M, Poleszak E.
Chair and Department of Applied Pharmacy, Medical University of Lublin, Chodźki 1, PL 20-093 Lublin, Poland. ewa.poleszak at umlub.pl; michal.skalski at wum.edu.pl.
Magnesium is one of the most essential mineral in the human body, connected with brain biochemistry and the fluidity of neuronal membrane. A variety of neuromuscular and psychiatric symptoms, including different types of depression, was observed in magnesium deficiency. Plasma/serum magnesium levels do not seem to be the appropriate indicators of depressive disorders, since ambiguous outcomes, depending on the study, were obtained. The emergence of a new approach to magnesium compounds in medical practice has been seen.
Apart from being administered as components of dietary supplements, they are also perceived as the effective agents in treatment of
- migraine,
- alcoholism,
- asthma,
- heart diseases,
- arrhythmias,
- renal calcium stones,
- premenstrual tension syndrome etc.
Magnesium preparations have an essential place in homeopathy as a remedy for a range of mental health problems. Mechanisms of antidepressant action of magnesium are not fully understood yet. Most probably, magnesium influences several systems associated with development of depression. The first information on the beneficial effect of magnesium sulfate given hypodermically to patients with agitated depression was published almost 100 years ago. Numerous pre-clinical and clinical studies confirmed the initial observations as well as demonstrated the beneficial safety profile of magnesium supplementation. Thus, magnesium preparations seem to be a valuable addition to the pharmacological armamentarium for management of depression.
Table in the PDF
PMID: 23950577
PDF is attached at the bottom of this page
See also VitaminDWiki
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- Depression is associated with low Magnesium – meta-analysis April 2015
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See also web
- A Cure for Depression using Magnesium? huge web page
Which has the following chart
Magnesium reduces depression etc. – Aug 20139153 visitors, last modified 14 Oct, 2015, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 5538 Mg and depression.jpg admin 30 May, 2015 107.58 Kb 1195 2916 Magnesium, depresssion, etc.pdf admin 23 Aug, 2013 129.01 Kb 1705 - Depression category listing has